British National Formulary 61 by Bma

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Additional resources for British National Formulary 61

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For most drugs the adult maximum dose should not be exceeded. For example if the dose is stated as 8 mg/kg (max. 300 mg), a child weighing 10 kg should receive 80 mg but a child weighing 40 kg should receive 300 mg (rather than 320 mg). Many children are able to swallow tablets or capsules and may prefer a solid dose form; involving the child and parents in choosing the formulation is helpful. Young children may require a higher dose per kilogram than adults because of their higher metabolic rates.

1), may be useful. Intractable cough Intractable cough may be relieved by moist inhalations or by regular administration of oral morphine in an initial dose of 5 mg every 4 hours. 1. m. to reduce the risk of insomnia. Restlessness and confusion Restlessness and confusion may require treatment with haloperidol 1–3 mg by mouth every 8 hours. Levomepromazine is also used occasionally for restlessness. For the dose by subcutaneous infusion using a continuous infusion device, see p. 23. BNF 61 Continuous infusion devices Although drugs can usually be administered by mouth to control the symptoms of advanced cancer, the parenteral route may sometimes be necessary.

However, there is a theoretical possibility that a small amount of drug present in breast milk can induce a hypersensitivity reaction. A clinical effect can occur in the infant if a pharmacologically significant quantity of the drug is present in milk. g. fluvastatin), the ratio between the concentration in milk and that in maternal plasma Where care is needed when prescribing in breast-feeding, this is indicated under the relevant drug in the BNF. For many drugs insufficient evidence is available to provide guidance and it is advisable to administer only essential drugs to a mother during breast-feeding.

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