Concise Dictionary of Pharmacological Agents: Properties and by Ian Dr Morton;Judith M. Hall;I. K. Morton

By Ian Dr Morton;Judith M. Hall;I. K. Morton

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ANTISCHISTOSOMES are drugs used to treat schistosomiasis (or bilharziasis) a tropical disease caused by blood flukes of the genus Schistosoma (class Trematoda of the phylum Platyhelminthes). In their life cycle and the drugs used to treat infection, they are similar to other helminths, and more details of the drugs are to be found at ANTHELMINTICS. Three drugs are used to treat infected humans. Praziquantel is a wide-spectrum anthelmintic, and used for all three species. Metriphonate is a drug of first choice for 5.

ANTITHROMBINS are agents that inhibit thrombin, which is a serine protease enzyme that has a central role in both thrombosis (the process that forms blood thrombi) and in haemostasis (the control of bleeding from blood vessels). There are a number of ways in which such ANTICOAGULANT agents may act. Indirect antithrombins. The action of heparin is complex, and it is sometimes referred to as an indirect-acting antithrombin, in as much as it works indirectly to inhibit the action of thrombin in the coagulation cascade.

R. (1993) Sickle cell disease: recent advances. Curr. Probl. , 23,219-29. W. et al. (1996) Clinical Pharmacology for Pediatricians. II. Antisickling agents, with special reference to new vasoerythroactive drugs. / CHn. ,22, 1-13. g. in the intestine, bladder and airways. The term is used in a rather general way in pharmacology and therapeutics, so many drugs can be regarded as antispasmodic, depending on the circumstances. Some drugs used to reduce spasm in smooth muscle are SMOOTH MUSCLE RELAXANTS.

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