Desk Encyclopedia of Microbiology, Second Edition by Moselio Schaechter

By Moselio Schaechter

The table Encyclopedia of Microbiology, moment version is a single-volume complete advisor to microbiology for the complicated reader. Derived from the six quantity e-only Encyclopedia of Microbiology, 3rd variation, it bridges the distance among introductory texts and really good reports. masking subject matters starting from the fundamental technological know-how of microbiology to the present "hot" subject matters within the box, it will likely be worthy for acquiring history details on a extensive variety of microbiological subject matters, getting ready lectures and getting ready supply functions and stories.

* the main complete single-volume resource delivering an summary of microbiology to non-specialists
* Bridges the space among introductory texts and really expert studies.
* presents concise and normal overviews of significant issues in the box making it a important source whilst getting ready for lectures, writing studies, or drafting supply purposes

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D) Type 1 pili-mediated attachment of uropathogenic E. coli (UPEC) to the luminal surface of the bladder epithelium. (Top) High-resolution, freezefracture, deep-etch electron micrograph is from Mulvey MA, Lopez-Boado YS, Wilson CL, et al. (1998) Induction and evasion of host defenses by type 1-piliated uropathogenic E. coli. Science 282: 1494–1497. Reprinted with permission from AAAS. (Bottom) Scanning electron micrograph of a bacterium entering the membrane of bladder epithelial cells is reprinted from Soto GE and Hultgren SJ (1999) Bacterial adhesins: Common themes and variations in architecture and assembly.

Indeed, the microbiota is dynamic and shifts in balance that alter the sizes of different bacterial populations can also lead to proliferation of disease-causing opportunistic pathogens. In addition, the inoculation of the human host with bacteria from the environment is a common source of infectious disease, particularly in the hospital setting. The consequences of bacterial adhesion in human infectious diseases are numerous and will be addressed in more detail after the description of specific adherence mechanisms.

Other adhesins recognize specific amino acid-recognition motifs in proteins expressed on host cell surfaces. Extracellular matrix (ECM) proteins that are not directly integrated into the host cell also serve as attractive binding platforms for many bacteria, and numerous adhesins bind to these components in order to indirectly hijack the host signaling pathways, often to enable host cell internalization. Another general category of adhesins includes nonproteinaceous molecules such as lipopolysaccharides and teichoic acids, synthesized by Gram-negative and Gram-positive bacteria, respectively.

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